Key drivers of migraine disease progression

At EAN 2022, Gisela Terwindt, Professor of Neurology, Leiden University Medical Centre, discussed key drivers for migraine progression including genetically-determined comorbidities of depression and anxiety; allodynia, where the head and other parts of the body are painful to touch; and medication overuse headache, wherein a vicious cycle can develop when a patient strives to take enough medication to relieve their symptoms but chronic use of such medication causes headache.